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Aij-Lie Kwan Selected Research

Intracranial Vasospasm

6/2022Therapeutic Effect of Mitochondrial Division Inhibitor-1 (Mdivi-1) on Hyperglycemia-Exacerbated Early and Delayed Brain Injuries after Experimental Subarachnoid Hemorrhage.
1/2021Attenuation in Proinflammatory Factors and Reduction in Neuronal Cell Apoptosis and Cerebral Vasospasm by Minocycline during Early Phase after Subarachnoid Hemorrhage in the Rat.
1/2015Arctigenin, a Potent Ingredient of Arctium lappa L., Induces Endothelial Nitric Oxide Synthase and Attenuates Subarachnoid Hemorrhage-Induced Vasospasm through PI3K/Akt Pathway in a Rat Model.
1/2014Alteration of basilar artery rho-kinase and soluble guanylyl cyclase protein expression in a rat model of cerebral vasospasm following subarachnoid hemorrhage.
1/2013Attenuation of cerebral vasospasm following experimental subarachnoid hemorrhage by the bronchodilator KMUP-3.
12/200917Beta-estradiol activates adenosine A(2a) receptor after subarachnoid hemorrhage.
7/2008Upregulation of estrogen receptor alpha and mediation of 17beta-estradiol vasoprotective effects via estrogen receptor alpha in basilar arteries in rats after experimental subarachnoid hemorrhage.
6/2007The adenosine 2A receptor agonist ATL-146e attenuates experimental posthemorrhagic vasospasm.
3/2007Attenuation of experimental subarachnoid hemorrhage--induced cerebral vasospasm by the adenosine A2A receptor agonist CGS 21680.
3/2007Attenuation of experimental subarachnoid hemorrhage-induced increases in circulating intercellular adhesion molecule-1 and cerebral vasospasm by the endothelin-converting enzyme inhibitor CGS 26303.
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Aij-Lie Kwan Research Topics

Disease

36Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
06/2022 - 02/2002
17Intracranial Vasospasm
06/2022 - 08/2002
16Neoplasms (Cancer)
05/2021 - 04/2005
10Inflammation (Inflammations)
06/2022 - 06/2007
8Astrocytoma (Pilocytic Astrocytoma)
01/2022 - 02/2013
6Brain Injuries (Brain Injury)
06/2022 - 08/2010
6Brain Neoplasms (Brain Tumor)
04/2017 - 09/2004
5Burns
01/2020 - 06/2014
4Stroke (Strokes)
11/2021 - 02/2006
4Glioma (Gliomas)
10/2021 - 04/2010
4Glioblastoma (Glioblastoma Multiforme)
05/2021 - 07/2019
4Traumatic Brain Injuries (Traumatic Brain Injury)
10/2015 - 06/2013
3Hyperglycemia
06/2022 - 05/2017
3Infarction (Infarctions)
11/2021 - 11/2004
3Brain Ischemia (Cerebral Ischemia)
09/2021 - 02/2007
3Atrophy
01/2020 - 01/2015
3Hyperalgesia
11/2018 - 08/2011
3Neuralgia (Stump Neuralgia)
07/2016 - 08/2011
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
08/2010 - 11/2004
2Carcinogenesis
07/2019 - 04/2017
2Pain (Aches)
11/2018 - 07/2016
2Brain Abscess (Abscess, Brain)
01/2014 - 09/2004
2Paraplegia (Spastic Paraplegia)
01/2014 - 02/2007
2Necrosis
01/2014 - 01/2013
2Ischemic Stroke
11/2011 - 11/2004
2Reperfusion Injury
02/2007 - 11/2004
2Vascular Remodeling
06/2006 - 11/2004
1Diabetes Mellitus
06/2022
1Meningioma (Meningiomas)
01/2021

Drug/Important Bio-Agent (IBA)

14Endothelin-1 (Endothelin 1)IBA
09/2021 - 08/2002
12Proteins (Proteins, Gene)FDA Link
09/2021 - 04/2010
9Biomarkers (Surrogate Marker)IBA
01/2022 - 03/2016
7CGS 26303IBA
07/2016 - 02/2002
7Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
01/2015 - 11/2004
6Endothelin-Converting EnzymesIBA
03/2007 - 08/2002
5salicylhydroxamic acid (SHAM)IBA
01/2020 - 06/2006
5Messenger RNA (mRNA)IBA
06/2015 - 11/2004
5Endothelins (Endothelin)IBA
06/2006 - 02/2002
4E-SelectinIBA
01/2015 - 09/2005
3CytokinesIBA
11/2021 - 08/2010
3Caspase 3 (Caspase-3)IBA
11/2020 - 07/2019
3MetalsIBA
01/2018 - 06/2014
3HMGB1 Protein (HMG1)IBA
02/2016 - 01/2014
3Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
01/2015 - 03/2007
3Interleukin-6 (Interleukin 6)IBA
01/2014 - 08/2010
3Neuroprotective AgentsIBA
03/2009 - 11/2004
3Peptides (Polypeptides)IBA
06/2006 - 08/2002
2Therapeutic UsesIBA
06/2022 - 08/2010
2Indicators and Reagents (Reagents)IBA
01/2022 - 09/2018
2Phosphotransferases (Kinase)IBA
10/2021 - 01/2014
2CateninsIBA
05/2021 - 05/2021
2ImmunosorbentsIBA
01/2021 - 06/2012
2EnzymesIBA
01/2021 - 06/2012
2Streptozocin (Streptozotocin)FDA Link
11/2020 - 05/2017
2CaspasesIBA
11/2020 - 01/2020
2ErythropoietinFDA Link
01/2020 - 01/2018
2Transforming Growth Factor beta (TGF-beta)IBA
01/2020 - 02/2013
2Small Interfering RNA (siRNA)IBA
07/2019 - 04/2017
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2019 - 04/2017
2Cyclin D1IBA
07/2019 - 04/2017
2lithospermate BIBA
10/2015 - 11/2011
2Glycyrrhizic Acid (Glycyrrhizin)IBA
01/2015 - 01/2014
2DNA (Deoxyribonucleic Acid)IBA
06/2014 - 01/2013
2rho-Associated KinasesIBA
01/2014 - 01/2014
2Vasoconstrictor AgentsIBA
01/2014 - 10/2006
2KMUP 1IBA
10/2012 - 08/2012
2Potassium Channels (Potassium Channel)IBA
10/2012 - 08/2012
2Nitric Oxide Synthase (NO Synthase)IBA
04/2011 - 08/2010
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
05/2010 - 03/2007
2Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
12/2009 - 03/2007
2Monoclonal AntibodiesIBA
06/2007 - 09/2005
2Neprilysin (Neutral Endopeptidase)IBA
07/2004 - 02/2002
1Blood Glucose (Blood Sugar)IBA
06/2022
13- (2,4- dichloro- 5- methoxyphenyl)- 2- sulfanyl- 4(3H)- quinazolinoneIBA
06/2022
1hepatoma-derived growth factorIBA
01/2022
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2021
1atrial natriuretic factor prohormone (31-67)IBA
09/2021
1Histone Deacetylases (Histone Deacetylase)IBA
05/2021
1Temozolomide (Temodar)FDA LinkGeneric
05/2021
1Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA
01/2021
1triphenyltetrazoliumIBA
01/2021
1B355252IBA
01/2021
1(2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oic acid) trifluoroethylamideIBA
01/2021
1Minocycline (Cyclops)FDA LinkGeneric
01/2021
1bardoxoloneIBA
01/2021
1fluorocitrateIBA
01/2021
1Transcription Factors (Transcription Factor)IBA
01/2021
1Caspase 9IBA
11/2020
1human AOC3 proteinIBA
04/2020

Therapy/Procedure

5Therapeutics
09/2021 - 05/2012
4Radiotherapy
01/2021 - 05/2012
4Craniotomy
01/2014 - 09/2002
3Ligation
07/2016 - 08/2011
2Drug Therapy (Chemotherapy)
04/2017 - 05/2012
2Denervation
08/2015 - 01/2015
2Operative Surgical Procedures
02/2014 - 01/2005
2Decompressive Craniectomy
09/2013 - 06/2013
2Laminectomy
05/2012 - 04/2005
2Intravenous Infusions
06/2006 - 11/2004
1Chemoradiotherapy
05/2021